Acne
Acne vulgaris
Clinical
In general, acne is limited to parts of the body, which have the largest and most abundant sebaceous glands like the face, neck, chest, upper back and arms. Among dermatologists, is almost universally accepted that the clinical manifestations of acne vulgaris is the result of four core processes that are described below:
1. Increased production of sebum in the pilosebaceous follicle. Tallow is the product of lipid-rich sebaceous gland secretion, which has a central role in the development of acne and also provides a medium for Propionibacterium acnes (P acnes), an anaerobic bacterium is a normal constituent skin flora. Compared to unaffected people, people with acne have higher rates of sebum production. Apart from this, the severity of acne is often proportional to the amount of sebum produced.
2. Abnormal follicular differentiation, which is the earliest structural changes in the pilosebaceous unit in acne vulgaris.